CNS depressants, sometimes referred to as sedatives and tranquilizers, are substances that can slow brain activity.This property makes them useful for treating anxiety and sleep disorders.A prudent practitioner should be capable of rescuing a patient from one level of sedation higher than is intended (e.g.rescuing from moderate sedation when performing minimal sedation).
The response to sedation in patients who are HIV-positive is unpredictable. American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients. 2011;1442-1350 [Cross Ref] Abbott Laboratories Ltd Abbott Laboratories Ltd Summary of product characteristics for Kaletra 200/50 mg tablets.Over-sedation can increase time on ventilatory support, prolong ICU stay, and may precipitate unnecessary neurological investigations., Sedation should be tailored to the individual needs of the patient.A combination of drugs is often required., A continuous infusion of a benzodiazepine has been identified as an independent predictor of a longer duration of mechanical ventilation, stay in the intensive care unit and stay in hospital., Sedation scores should be used to allow titration of drug administration., The sedation ‘holiday’ strategy has been shown to decrease the duration of mechanical ventilation and length of stay in ICU.: In Ontario, a practitioner who intends to use a single drug to achieve minimal sedation must monitor patients by “clinical observation of the level of consciousness and assessment of vital signs which may include heart rate, blood pressure, and respiration” (Ontario’s Standards of Practice for the ).If the practitioner were to change modalities of sedation or increase their sedative dosage with the intent of achieving moderate sedation, so too would the monitoring requirements increase (i.e.