She was hired for a single episode guest appearance on The Bernie Mac Show in 2002, but she was brought back to work on a further ten episodes throughout all five seasons.
In 2009, Rivera was cast as Santana Lopez, a high school cheerleader, on Fox's musical comedy series Glee, about a high school glee club.
In 2002, she also appeared in the music video for B2K's "Why I Love You".
In Frenemies, she is cast as Rachel's understudy in Funny Girl, starting a feud between them that gets both Rachel and Santana kicked out of Kurt's band, previously named Pamela Lansbury, now called One Three Hill.
In New Directions she resigned as the understudy of Rachel in Funny Girl .
Brittany and Santana had a 'best-friends with benefits' arrangement.
This was hinted at in various instances in Season 1, but it was was made official in Season 2, when the two were seen making out (Duets).