She has two older sisters named Kathy and Karen and a younger brother named Steven.While studying at Kennett High School, Crow was a majorette and an all-state track athlete, medaling in the 75-meter low hurdles.
“When I was diagnosed with cancer I moved [from Los Angeles to Nashville] as I wanted to put down roots and nurture my life in a way that I hadn’t before.
"But what ends up happening is that one of you becomes smaller — and it was always me. I mean, I don't know if it's the woman, but I do think that sometimes in order for one person's light to shine, everyone else has to dim theirs."The same was true with former fiancé Lance Armstrong with whom she found herself feeling "really small," admitting she became a "self-appointed caretaker" who was always checking to make sure that "everyone else was OK, everyone else was happy."Five months after the pair announced their engagement in 2005, the duo went their separate ways, and shortly after, Crow was diagnosed with breast cancer.
After successfully beating the disease, the singer decided to move to Nashville in order to be closer to her family and ultimately came to the realization that she wanted to start a family of her Crow adopted sons Wyatt, now 7, in 2007 and Levi, now 4, in 2010.
In 1987-'88 she sang on Michael Jackson’s "Bad" world tour.
She later sang back-up for Sting, Rod Stewart and Don Henley.